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Trial Evaluating PCSK9 Antibody in Subjects With LDL Receptor Abnormalities (TESLA). The safety and scientific validity of this study is the responsibility. These assays can measure PC9/PCSK9 alone or in multiplex panels with other biomarkers. The Product Inserts for R-PLEX Antibody Sets provide detailed. Neutralizing recombinant human antibody (IgG1) recognizing the LDLR binding region of human PCSK9.

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PCSK9 is a key regulator of LDL-cholesterol levels (LDL-C) through binding of the LDL receptor, resulting in the reduction of receptor recycling to the cell. Monoclonal Antibody for studying PCSK9. Cited in 5 publications. Validated for Western Blotting, Immunoprecipitation. Highly specific and rigorously. Regeneron's general counsel Joseph LaRosa said in a statement the decision "affirms our longstanding position that Amgen's patents claiming PCSK9 antibodies.

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PCSK9 Proteins, Antibodies, cDNA Clones, ELISA Kits Research Reagents. PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) is a protein coding gene located on. PCSK9 is a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein is synthesized as a soluble zymogen. Just like evolocumab in Repatha, the substance alirocumab used in Praluent is a monoclonal antibody protein that attaches to the PCSK9 gene.